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These investigators did not rank 17α-methyltestosterone, but it had a relative binding affinity of 0. The relative binding with fluoxymesterone, methandienone and stanozolol was much weaker and that with oxymetholone and ethylestrenol was too low to be determined. There is a large discrepancy as to what is known about the in vivo activities of these steroids compared with their in vitro activity, even taking into account possible differences in the bioavailability and clearance of these steroids (not least determined by the affinity to sex hormone-binding globulin in the blood circulation). For example, oxymetholone and stanozolol have low relative binding affinity compared with 17α-methyltestosterone in the in vitro study, but, conversely, these steroids have a relatively high myotrophic activity compared with the same steroid when administered to the castrated rat (see Table 1 ), dianabol 20 para pharma. Furthermore, Feldkoren and Andersson (2005) found that stanozolol and methandienone have significantly lower binding affinities compared with testosterone but all three steroids were potent activators in a cell-based androgen receptor-dependent transactivation assay.
The rat levator ani muscle is part of the perineal complex of striated muscles that envelope the rectum, dianabol 20 para pharma.
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