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It was in the 1930s when the core component/ingredient that originated in the testicles, which was responsible for all of these traits was discovered: Testosterone. Adolf Butenandt identified, isolated, and synthesized Testosterone in the early 1930s, which would forever change many aspects of medicine, and of course athletics. Following the isolation and identification of Testosterone, research and testing continued in order to manipulate the properties of the hormone, methanabol 10 mg oral steroids dianabol. Upon its first isolation, the very first preparations of Testosterone created (Testosterone suspension) were crude and impractical for regular use. Testosterone on its own, pure and unmodified in any way, expressed properties that were too inconvenient and impractical for regular clinical, medical, or even athletic use. First of all, being that it is not very soluble in oil, it had to be suspended in water within microcrystals. Such an injection preparation, known as Testosterone suspension, was far too painful to inject on a regular basis. Furthermore, the half-life of pure Testosterone is approximately 6 ‘ 12 hours, which necessitated either daily or multiple times per day injections. It was not long afterwards during the 1930s that it was discovered that different carboxylic acids could be bonded (via ester bonding) onto the 17-beta hydroxyl group of the steroid structure, which would extend the half-life and release rate of the hormone. The shorter the ester bond, the shorter the half-life is granted to the hormone. The longer the ester bond, the longer the half-life. One of the first esterified formats of Testosterone (also known as a Testosterone ester) was Testosterone Propionate, a fast acting variant that exhibits a half-life of 4. Although this was much longer than pure Testosterone’s half-life, it was still not very practical for medical use. 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There were also developments of products which contained blends of different Testosterone esters, such as Sustanon 250 and Omnadren. The availability of different types of Testosterone products for athletes and bodybuilders is very extensive. Contrary to what might be commonly touted in internet message boards, forums, and common chatter among anabolic steroid users in gyms, the ester that is affixed to Testosterone (or any anabolic steroid for that matter) serves only to augment the release rate and half-life of the hormone. Esterification does nothing to alter the pharmacology of the hormone itself within the human body. In order for that to occur, direct modifications to the integral parts of the chemical structure itself must occur, which would result in Testosterone becoming a new anabolic steroid ‘ it would no longer be Testosterone any more. 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