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15,30 A recent study found that the anabolic steroid use was associated with an increased prevalence of hip fractures and other osteoporotic fractures, . 9 Use of hormonal contraceptives during adolescence may increase bone density. 9 Osteocalcin is a metabolite of the endogenous anabolic steroid dihydrotestosterone (DHT), which plays roles in the growth of bone and is responsible for growth hormone release and bone formation. 4 The increased osteocalcin production may prevent the bone formation induced by anabolic steroids use in adolescent athletes. Another osteocalcin derivative, 5-O-methyl-O-m-dibenzo[a]pyrene (DibENP), that is produced after DHT is metabolized to dihydrotestosterone is associated with bone resorption in bone-wasting conditions.

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